A Phase II Trial Neoadjuvant Paclitaxel and Cisplatin in Patients With Locally Advanced Head and Neck Cancer

• Status: Completed
• Trial end date: 2007-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this clinical research study is to learn if a paclitaxel-cisplatin combination regimen given in the neoadjuvant setting is active in locally advanced head and neck cancer. the safety of this treatment will also be studied.

• Phase: Phase 2/Phase 3

Details

• Lead Sponsor: Bristol-Myers Squibb
• Treatments: Albumin-Bound Paclitaxel; Cisplatin; Paclitaxel

Criteria

Inclusion Criteria:

• Locally advanced, Stage II-IV (except M1), hand and neck cancer

• > = 1 measurable lesion

• not been previously treated for head and neck cancer

Exclusion Criteria:

• history of another malignancy

• organ allografts

• pre-exiting neuropathy > = CTC grade 2