A Phase IV Study Investigating the Effects of Remifentanil Concentrations on Propofol Requirements for Loss of Consciousness, Response to Painful Stimuli, Bispectral Index and Associated Haemodynamic Changes

• Status: Completed
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: All

Summary

A prospective, randomised, phase IV trial including 150 patients.

To evaluate the effects of varied concentrations of remifentanil on the proposal requirements for the loss of consciousness and response to pain and to evaluate the haemodynamic changes and processed EEG (BIS) during induction of anaesthesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The University of Hong Kong
• Treatments: Propofol; Remifentanil

Criteria

Inclusion Criteria:

ASA I or II patients (healthy or with mild systemic illness) undergoing planned surgery requiring general anaesthetic

Exclusion Criteria:

1. Subjects with pre-existing neurological or psychiatric illness.

2. Subjects on CNS acting medication or analgesics.