A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.
Status:
RECRUITING
Trial end date:
2025-12-30
Target enrollment:
Participant gender:
Summary
To evaluate the safety and tolerability of peguricase for injection with methotrexate in patients with gout who remain uncontrolled after standardized treatment with conventional uric acid-lowering drugs, to determine the recommended dose for phase II clinical trials, and to provide basis for formulation of administration regimen for phase II clinical trials.
Phase:
PHASE1
Details
Lead Sponsor:
Shanghai Institute Of Biological Products
Collaborators:
Chengdu Fifth People's Hospital The First Affiliated Hospital of Bengbu Medical University The First Affiliated Hospital of Henan University of Science and Technology