A Pilot Drug Trial That Evaluates the Whitening Potential of Nicotine Gum

• Status: Completed
• Trial end date: 2005-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research study is to evaluate the effects on existing tooth stain of nicotine gum. The study will enroll adults who have visible tooth staining.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: McNeil AB
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• daily smokers for at least one year

• motivated to quit smoking

• normal chewing ability

• willing to refrain from a dental prophylaxis for the duration of the study

• total extrinsic facial tooth stain score > or = to 28, according to the MacPherson Modification of the Lobene Stain Index

Exclusion Criteria:

• < 20 natural teeth

• inadequate oral hygiene