A Pilot Study Using 18F-DOPA PET-guided Radiotherapy in Gliomas
Status:
Active, not recruiting
Trial end date:
2031-03-01
Target enrollment:
Participant gender:
Summary
For most brain tumors, radiation treatment is guided by a Magnetic Resonance Imaging (MRI)
scan. In this study, information from a special scan, called a Positron Emission Tomography/
Computed Tomography (PET/CT) scan using an amino acid called
Fluorine-18-L-dihydroxyphenylalanine (18F-DOPA) will also be used. This type of scan has
shown promise in being able to better distinguish tumor from normal brain tissue and may help
to more accurately plan radiation treatment. This type of scan can also assist the radiation
oncologist in identifying the most aggressive regions of the tumor. The goal of this study is
to compare the 18F-DOPA PET/CT scan with the MRI scan for identifying where the disease is
that needs to be treated with radiation.