A Pilot Study for Optimizing Meropenem Administration in the ICU
Status:
Recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
Can antibiotic drugs be administered faster and make acceptable serum concentrations if we
give short but multiple infusions compared to long and fewer infusions? In this study we will
compare giving meropenem 1 gram 6 times daily in 15 minutes infusions to the recommended 2
gram 3 times daily in 3 hours infusions. In patients in the intensive care unit, the need for
intravenous access is of essence. If 6 short infusions results in the same serum
concentrations as 3 long infusions, we will increase intravenous access from 15 to 22.5 hours
daily.