A Pilot Study of Acarbose as Treatment for Pediatric Non-alcoholic Fatty Liver Disease (NAFLD)
Status:
Terminated
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to demonstrate a reduction of intrahepatic fat as measured
with Proton Magnetic Resonance Spectroscopy after 12 weeks administration of oral acarbose.
The study will also examine the hypothesis of whether the chronic administration of acarbose
in patients with NAFLD will influence postprandial substrate metabolism reflected in the RQ
measured by indirect calorimetry.