Overview

A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

Status:
Terminated
Trial end date:
2015-07-31
Target enrollment:
Participant gender:
Summary
This is a pilot study using decitabine and vorinostat before and during chemotherapy with vincristine, dexamethasone, mitoxantrone, and peg-asparaginase in pediatric patients with acute lymphoblastic leukemia (ALL).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Therapeutic Advances in Childhood Leukemia Consortium
Treatments:
Asparaginase
Azacitidine
BB 1101
Decitabine
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Methotrexate
Mitoxantrone
Pegaspargase
Vincristine
Vorinostat