A Pilot Study of Effect of Dexmedetomidine on Sleep and Inflammation in Critically Ill Patients

• Status: Completed
• Trial end date: 2007-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess the short-term effect of sympatholysis on sleep quality and inflammation in critically ill patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Arizona
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• Patients requiring mechanical ventilation with a diagnosis of

• Acute Respiratory Distress Syndrome

• Cardiogenic Pulmonary Edema

• Pneumonia

• Chronic obstructive pulmonary disease

Exclusion Criteria:

• Patients who are considered too unstable to undergo this investigation by their primary physician

• Comatose patients, or patients with severe debilitating neurological disease

• Renal insufficiency (Sr. Creatinine > 2 mg/dL)

• Heart block (second or third degree heart block) or sinus bradycardia (heart rate < 60 beats per minute)

• Pregnancy