A Pilot Study of FOLFIRINOX in Combination With Neoadjuvant Radiation for Gastric and GE Junction Cancers

• Status: Active, not recruiting
• Trial end date: 2023-06-30

Summary

This research study is studying a combination of interventions as a possible treatment for gastroesophageal (GE) junction cancer.

The interventions involved in this study are:

-FOLFIRINOX which is made up of 4 different drugs:

• 5-Fluorouracil (5-FU)

• Oxaliplatin

• Irinotecan

• Leucovorin

• Paclitaxel

• Carboplatin

• Proton Beam Radiation Therapy

• Phase: Phase 1

Details

• Lead Sponsor: Massachusetts General Hospital
• Collaborator: National Cancer Institute (NCI)
• Treatments: Carboplatin; Fluorouracil; Irinotecan; Leucovorin; Oxaliplatin; Paclitaxel