A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for Hypertension
Status:
Completed
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate the effect of plasma renin activity-guided
therapy for determining hypertension treatment. Plasma renin is an enzyme in your blood that
can be measured to determine your hypertension subtype. Once the subtype is known, doctors
can prescribe specific medications to target your specific hypertension subtype. This study
will investigate whether targeting the specific hypertension subtype helps to achieve blood
pressure control sooner and with fewer medications compared to a standard fixed dose
combination therapy.
Phase:
N/A
Details
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborators:
Cornell University Wake Forest University Health Sciences
Treatments:
Amlodipine Hydrochlorothiazide Hydrochlorothiazide, lisinopril drug combination Lisinopril Metoprolol