A Pilot Study of Triple NtRTI/NsRTI Therapy in Antiretroviral Naive HIV-1 Infected Patients
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the antiviral effect and durability of antiviral
response (HIV-1 RNA PCR) and safety of a triple NtRTI/NsRTI therapy in antiretroviral naive
patients. Patients will receive TDF plus FTC plus AZT for at least 48 weeks. Further
objectives are to evaluate resistance pathways in failing patients treated with TDF/FTC/AZT
and to evaluate a treatment strategy of sparing PIs and NNRTIs for later treatment.