A Pilot Study on Fertility Conservative Treatment of Atypical Endometrial Hyperplasia in Singapore

• Status: Recruiting
• Trial end date: 2023-03-31
• Target enrollment: 0
• Participant gender: Female

Summary

The investigators' objective is to determine the regression rate, side effects and acceptability of Mirena compared to megace in the treatment of atypical endometrial hyperplasia among women desiring fertility.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: KK Women's and Children's Hospital
• Treatments: Levonorgestrel; Megestrol Acetate

Criteria

Inclusion Criteria:

• All women diagnosed with atypical hyperplasia aged 21 years to 40 years

• Keen for fertility-preserving treatment

Exclusion Criteria:

• Patients who are currently undergoing treatment for atypical hyperplasia

• Patients with a history of endometrial carcinoma