A Pilot Study to Evaluate Efficacy and Safety of Clevidipine in Neurosurgical Patients
Status:
Completed
Trial end date:
2010-02-01
Target enrollment:
Participant gender:
Summary
This protocol describes a study to gain experience in the use of Clevidipine for
perioperative blood pressure control in patients undergoing craniotomy for brain tumor or
epilepsy focus resection. The purpose of this study is to establish the efficacy of
Clevidipine for intraoperative blood pressure control in patients undergoing intracranial
procedures, and gather information on the dosage and adverse effects of Clevidipine in
neurosurgical patients. This initial pilot experience serves to familiarize the investigators
with the use of this drug prior to initiating a planned randomized trial versus institutional
standard-of-care therapy. The investigators will obtain greater familiarity with the dosing
of clevidipine in this patient population and collect information on the incidence of adverse
effects.
Phase:
Phase 4
Details
Lead Sponsor:
New York University School of Medicine NYU Langone Health