A Pilot Trial of Twice-weekly Versus Thrice-weekly Hemodialysis in Patients With Incident End-stage Kidney Disease
Status:
Recruiting
Trial end date:
2023-06-01
Target enrollment:
Participant gender:
Summary
The optimal frequency of hemodialysis treatments in patients with incident end-stage kidney
disease in not known. This pilot trial will randomize patients with incident end-stage kidney
disease due to chronic kidney disease progression to two different regimens of hemodialysis:
i) twice-weekly hemodialysis for six weeks with adjuvant pharmacologic medications followed
by thrice-weekly hemodialysis, or ii) thrice-weekly hemodialysis. The study will test
feasibility of stepwise hemodialysis, and the effects of the two regimens of hemodialysis on
residual kidney function.