A Prospective, Multicenter, and Exploratory Study of CMGV in the Treatment of Recurrent Adult AML and MDS-EB-2/Elder AML
Status:
RECRUITING
Trial end date:
2027-12-31
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial\] is to evaluate mitoxantrone hydrochloride liposomes, subcutaneous injection of cytarabine and G-CSF combined with Venetoclax (CMG+Ven) in adult secondary acute myeloid leukemia and myelodysplastic syndrome with increased primordial cells type 2(MDS-IB2) or elderly acute myeloid leukemia\]. The main questions it aims to answer are:
* Evaluation of the efficacy
* Evaluation of the safety
Phase:
NA
Details
Lead Sponsor:
Ruijin Hospital
Collaborators:
Army Medical Center of PLA Dalian Municipal Central Hospital First Hospital of China Medical University Huadong Hospital Huashan Hospital RenJi Hospital Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Shanghai Jiading District Central Hospital Shanghai Public Health Clinical Center Shanghai Pudong Hospital Shanghai Zhongshan Hospital Sun Yat-sen University Taizhou First People's Hospital The Affiliated People's Hospital of Ningbo University The Second Affiliated Hospital of Dalian Medical University Wenzhou People's Hospital Xuhui Central Hospital, Shanghai