A Prospective, Randomized TrialComparing Oral N-Acetylcysteine and Intravenous Sodium Bicarbonate

• Status: Unknown status
• Trial end date: 2011-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the efficacy of oral N-acetylcysteine and intravenous sodium bicarbonate for the prevention of CIN after cardiac catheterization.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Nebraska
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria: 19 years of age

• Baseline serum creatinine or

• Calculated creatinine

• Stable Renal Function

• Left Ventricular ejection fraction

• Non-pregnant, non-lactating females (all women of childbearing potential must have a negative serum pregnancy test. No contraception will be required

• Able to sign informed consent

Exclusion Criteria:

• Acute renal failure

• History of Kidney transplant

• Currently receiving N-acetylcysteine

_ Contraindication of hypersensitivity to N-acetylcysteine or sodium bicarbonate

• Left ventricular ejection fraction

• Pregnant, lactating females

• Allergy to contrast dye