Overview

A Prospective Study on the Tolerability and Efficacy of the de Novo Use of Myfortic in Liver Transplant Recipients

Status:
Completed
Trial end date:
2008-11-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to compare the safety and efficacy of Myfortic with CellCept in liver transplant patients. Myfortic and CellCept are both immunosuppressive (anti-rejection) drugs. CellCept is commonly used after liver transplantation but gastrointestinal (GI) side effects are very common, sometimes necessitating in its discontinuation. Myfortic is a new drug similar to CellCept, except it is enteric-coated. Our hypothesis is that Myfortic has less GI side effects than CellCept and also has comparable effectiveness to CellCept.
Phase:
N/A
Details
Lead Sponsor:
University of Pittsburgh
Collaborators:
Novartis
Novartis Pharmaceuticals
Treatments:
Mycophenolate mofetil
Mycophenolic Acid