A Randomized, Clinical Trial of Oral Midazolam Versus Oral Ketamine for Sedation During Laceration Repair.
Status:
Unknown status
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
Sedation is often needed for young children undergoing minor procedures in the emergency
department (ED). Oral midazolam is one of the most commonly used regimens for children
undergoing laceration repair but its sedative efficacy was shown to be suboptimal. In only
one randomized controlled study oral ketamine has been used successfully for procedural
sedation for laceration repair. A recent study showed that the combination of oral midazolam
and oral ketamine provided deeper sedation compared with oral midazolam alone. However
children treated wuth the combination of midazolam and ketamine required longer recovery
Hypothesis:
Oral ketamine can provide superior sedation to oral midazolam in children requiring sedation
for laceration repair.