A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planus

• Status: Unknown status
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the effect of topical Pimecrolimus with adcortyl on erosive-atrophic 0ral lichen planus in a randomized clinical trial study.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mashhad University of Medical Sciences
• Treatments: Pimecrolimus; Tacrolimus; Triamcinolone Acetonide

Criteria

Inclusion Criteria:

• Biopsy confirmed oral lichen planus in combination with a compatible clinical appearance was used for diagnosis.

Exclusion Criteria:

• Unable to undergo oral biopsy for diagnosis

• Systemic diseases or malignancy

• Pregnancy

• Lesion/lesions with dysplasia/ history of allergic reaction to corticosteroids or immunomodulatory drugs.

• Lesions adjacent to amalgam filling were also excluded from this study.