A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions
Status:
Completed
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
This study, a double blinded randomized controlled trial, is being done to compare side
effects of commonly used antibiotic regimens prior to same day abortion procedures.
In total, 180 pregnant women in their first trimester of pregnancy (5 0/6-13 6/7 weeks
gestation) will be randomized to receive one of the three commonly used antibiotics
(azithromycin, doxycycline, metronidazole) for same day abortion procedures or placebo prior
to their abortion procedure. Approximately, 30-60 mins after study drug administration, the
procedure will be performed.
A sub-study will be completed on 40 women who consent to endometrial sampling and to have
their blood drawn.