Overview A Randomized Study of Smile Exercise for Dry Eye Status: Enrolling by invitation Trial end date: 2021-03-30 Target enrollment: Participant gender: Summary The objective of the study is to evaluate the effectiveness of laughter therapy in relieving the symptoms of dry eye disease. Phase: N/A Details Lead Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen UniversityTreatments: Hyaluronic AcidOphthalmic Solutions