A Randomized Trial of 4% Nebulized Lignocaine vs. 10% Lignocaine Spray in Patients Undergoing Flexible Bronchoscopy

• Status: Completed
• Trial end date: 2018-06-30
• Target enrollment: 0
• Participant gender: All

Summary

Flexible bronchoscopy is common procedure used in the diagnosis and treatment of a variety of tracheobronchial diseases. During routine diagnostic flexible bronchoscopy, the most distressing symptom experienced by the patients is a cough, and control of a cough is vital for a successful procedure. The investigators hypothesized that either nebulized lignocaine or lignocaine spray given alone prior to flexible bronchoscopy for inducing topical anesthesia will have similar efficacy compared to the combination of the two agents.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Postgraduate Institute of Medical Education and Research
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Age ≥18 years

• Willing for flexible bronchoscopy procedure a

Exclusion Criteria:

• Requirement of intravenous sedation to undergo any procedure including EBUS-TBNA, conventional TBNA, radial EBUS procedure and interventional pulmonary procedures

• Sensitivity to lignocaine

• Hemodynamically unstable patients (SBP < 90 mm Hg)

• Baseline hypoxemia (SpO2 <92% on room air)

• Pregnancy

• Comorbid illness such as heart failure, CKD, chronic liver disease and others

• Failure to provide informed consent