A Research Study Examining The Use Of Duloxetine In The Prevention Of Migraine Headache
Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
This is a single-center, open-label, pilot trial to collect and evaluate data on the safety
and efficacy of duloxetine in the preventive treatment of subjects experiencing episodic
migraine headaches. Following a 28-day baseline period, qualifying subjects will be entered
into an 84-day treatment period. Subjects will be titrated over the first four weeks to a
dose of 120mg or their maximally tolerated dose (MTD). The dose adjustments will be based on
individual subject response and/or subject's tolerability. Subjects will maintain a daily
diary capturing detailed information on migraine headache days.