A Research Study to Evaluate MK0653 (Ezetimibe) and Simvastatin, Given Together and Alone, on Intestinal Absorption of Cholesterol (0653-050)(COMPLETED)

• Status: Completed
• Trial end date: 2004-04-01
• Target enrollment: 0
• Participant gender: Male

Summary

To determine the effect of ezetimibe and simvastatin given together, and ezetimibe and simvastatin given alone on intestinal cholesterol absorption.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Merck Sharp & Dohme Corp.
• Collaborator: Schering-Plough
• Treatments: Ezetimibe; Simvastatin

Criteria

Inclusion Criteria:

• Healthy males between the ages of 18-55 with LDL More than 130, but less than 180

Exclusion Criteria:

• Individuals with drug or substance abuse

• Individuals with poor mental function

• Individuals having more than 14 alcoholic drinks a week

• Individuals that have been treated with any other investigational drug in the last 30 days