A Research of Berberine Hydrochloride to Prevent Colorectal Adenomas in Patients With Previous Colorectal Cancer
Status:
Unknown status
Trial end date:
2021-03-01
Target enrollment:
Participant gender:
Summary
Experimental studies in animals and observational studies in humans suggest that
fusobacterium nucleatum is associates with stages of colorectal neoplasia development, and
Berberine Hydrochloride could rescue Fusobacterium nucleatum-induced colorectal tumorigenesis
by modulating the tumor microenvironment. Whether regular Berberine Hydrochloride use may
decrease the risk of colorectal adenomas, the precursors to most colorectal cancers is worth
to further study.