Overview A Safety, Efficacy and Biomarker Study of JNJ-42847922 in Participants With Major Depressive Disorder Status: Completed Trial end date: 2016-01-04 Target enrollment: Participant gender: Summary The purpose of this study is to evaluate the safety and tolerability of JNJ-42847922 in participants with Major Depressive Disorder (MDD). Phase: Phase 1 Details Lead Sponsor: Janssen-Cilag International NVTreatments: DiphenhydraminePromethazine