This is a safety extension study of DR-OXY-301 at pre-selected sites. Subjects who complete
the DR-OXY-301 study are eligible to participate. The duration of this extension study will
be up to approximately 42 weeks. Subjects will have physical and laboratory exams, including
blood draws at each scheduled visit and colposcopic examination of the vagina and cervix. As
in DR-OXY-301, subjects will be required to insert a vaginal ring; replacing it every 4
weeks. Subjects will also be required to keep a daily record of the number of times and the
total amount of time the ring was outside the body each day and the reason for voluntary
removal.