Overview

A Safety Study of Carfilzomib, Cyclophosphamide & Dexamethasone Prior to ASCT in Patients With Newly Diagnosed Myeloma

Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
This is a dose finding pilot study to evaluate the safety and determine the maximum tolerated dose of the combination of carfilzomib and cyclophosphamide with dexamethasone (Car-Cy-Dex) prior to autologous stem cell transplant (ASCT) in patients with newly diagnosed transplant eligible multiple myeloma.
Phase:
Phase 1
Details
Lead Sponsor:
Academic Myeloma Consortium
Criterium, Inc.
Collaborators:
Amgen
Onyx Pharmaceuticals
Treatments:
BB 1101
Cyclophosphamide
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate