A Single and Multiple Ascending Dose Study of JNJ-64457744
Status:
Not yet recruiting
Trial end date:
2023-04-28
Target enrollment:
Participant gender:
Summary
The purpose of the study is to evaluate the safety and tolerability of: single ascending dose
(SAD) and multiple ascending dose (MAD) administration of JNJ-64457744, administered to
healthy adult participants (Part 1 and Part 3), including a cohort of Asian participants
(Part 1); and after single dose administration of JNJ-64457744 to chronic hepatitis B (CHB)
participants who are virologically suppressed on nucleos(t)ide analog (NA) treatment
(tenofovir disoproxil fumarate [TDF], tenofovir alafenamide [TAF], or entecavir [ETV]) (Part
2).