A Smoking Cessation Trial in HIV-infected Patients in South Africa

• Status: Completed
• Trial end date: 2017-06-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to conduct a randomized controlled trial (RCT) of intensive anti-smoking counseling plus nicotine replacement therapy versus intensive anti-smoking counseling alone among HIV-infected patients in South Africa, and to concurrently measure the prevalence of smoking among HIV-infected patients in South Africa.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Johns Hopkins University
• Collaborators: National Institute on Drug Abuse (NIDA); Truth Initiative; University of Witwatersrand, South Africa
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• Current, daily smoker (biochemically verified via a positive result on the SmokeScreen® test from GFC Diagnostics Ltd., as described in the outcomes)

• Be willing to set a quit date within 2 weeks after baseline assessment

• Agree to participate in study and anticipated to be attending Tshepong Wellness Clinic, Jouberton Community Health Center, or Grace Mokhomo Community Health Center (due to HIV infection) for at least 6 months

Exclusion Criteria:

• Pregnant or nursing

• Currently using smokeless tobacco (including electronic cigarettes, NRT or other cessation treatment)

• Tuberculosis confirmed case

• Weight <45 kg or BMI <20

• Suffering from any unstable medical condition which could preclude use of the nicotine patch:

• unstable angina

• uncontrolled hypertension

• active skin disease (e.g. psoriasis)

• history of skin allergy