Overview

A Study Combining ABT-888, Oral PARP Inhibitor, With Temozolomide in Patients With Metastatic Prostate Cancer

Status:
Completed
Trial end date:
2011-06-01
Target enrollment:
Participant gender:
Summary
Assess whether the combination of ABT-888 with temozolomide (TMZ) has activity in subjects with metastatic castration resistant prostate cancer (CRPC) as reflected by the prostate-specific antigen (PSA) response.
Phase:
Phase 1
Details
Lead Sponsor:
AbbVie (prior sponsor, Abbott)
Collaborator:
Prostate Cancer Clinical Trials Consortium
Treatments:
Dacarbazine
Poly(ADP-ribose) Polymerase Inhibitors
Temozolomide
Veliparib