A Study Comparing Etoposide/Cisplatin With Irinotecan/Cisplatin to Treat Extensive Disease Small Lung Cancer
Status:
Completed
Trial end date:
2013-10-01
Target enrollment:
Participant gender:
Summary
This study is a randomized, multi-center clinical trial. Patients are stratified according to
performance status (ECOG 0, 1 vs 2) and institution. Patients are randomized to 1 of 2
treatment arms.
Arm A: Patients receive etoposide IV on days 1, 2, 3 and cisplatin IV on day 1. Courses
repeat every 3 weeks Arm B: Patients receive irinotecan IV on days 1, 8 and cisplatin IV on
day 1. Coursed repeated every 3 weeks
Treatment in both arms continues for 6 courses in the absence of disease progression or
unacceptable toxicity.
Patients are followed every 3 months for 1.5 years