A Study Comparing High Dose Omeprazole Infusion Against Scheduled Second Endoscopy for Bleeding Peptic Ulcer

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

A prospective randomized study to compare the adjunctive use of high dose omeprazole infusion against scheduled second endoscopy in prevention of peptic ulcer rebleeding after therapeutic endoscopy.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chinese University of Hong Kong
• Treatments: Omeprazole

Criteria

Inclusion Criteria:

• all consecutive patients admitted for peptic ulcer bleeding (including bleeding anastomotic ulcers) with emergency endoscopy done in 24 hours after admission with Forrest type Ia, Ib, and IIa, IIb

• age 15 - 90 years

• Written consent available

Exclusion Criteria:

• ulcer bleeding not controlled in first endoscopy

• Bleeding from malignant ulcer or tumor

• Bleeding from Dieulafoy lesion/ angiodysplasia

• Bleeding from injection sclerotherapy ulcer

• Patient with ASA category 5