A Study Comparing Oral Calcitonin to Nasal Spray Calcitonin in Postmenopausal Osteoporotic Women
Status:
Completed
Trial end date:
2011-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the effectiveness and tolerability of two
medications, calcitonin nasal spray and a tablet containing calcitonin, in postmenopausal
women with osteoporosis. Osteoporosis is the term used to describe a large group of diseases,
which are characterized by loss of bone density, which makes the bones weaker. Osteoporosis
often occurs in postmenopausal women.
Calcitonin is a hormone found in the human body. Together with other substances, it regulates
the concentration of calcium in the blood and inhibits the natural resorption of bone. Both
medications in this study contain salmon calcitonin (sCT), because this form of calcitonin is
more active than human calcitonin when used as a medicine.
The calcitonin Nasal Spray used in this study is registered and available to doctors in
United States for the treatment of osteoporosis. The medication being tested in this study is
an oral tablet form of salmon calcitonin.