Overview

A Study Comparing Safety and Efficacy of Levofloxacin and Metronidazole Versus Piperacillin/Tazobactam in Treating Complicated Appendicitis

Status:
Terminated

Trial end date:
2004-09-01

Target enrollment:

Participant gender:

Summary

The purpose of this study is to compare the efficacy and safety of two treatment regimens in treating patients with complicated appendicitis. Appendicitis requires antibiotic treatment when the appendix ruptures (complicated appendicitis). This is a study comparing intravenous (IV) antibiotic therapy of levofloxacin/metronidazole versus piperacillin/tazobactam for 4 to 14 days. Patients may be switched to oral therapy after 48 hours, at the doctor's discretion.

Phase:

Phase 4

Details

Lead Sponsor:

Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Collaborator:

PriCara, Unit of Ortho-McNeil, Inc.

Treatments:

Levofloxacin
Metronidazole
Ofloxacin
Penicillanic Acid
Piperacillin
Piperacillin, tazobactam drug combination
Tazobactam