A Study Comparing Vaginal Misoprostol and Intravenous Oxytocin for Induction of Labor

• Status: Completed
• Trial end date: 2014-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study will compare the effectiveness of vaginal misoprostol (Cytotec) and intravenous oxytocin (Pitocin) in multiparous women who present at term for labor induction.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Vanderbilt University; Vanderbilt University Medical Center
• Treatments: Misoprostol; Oxytocin

Criteria

Inclusion Criteria:

• Clinical candidate for labor induction utilizing either misoprostol or oxytocin

• Greater than or equal to 18 years of age

• Multiparous

• Singleton gestation;

• Greater than 37 weeks gestation;

• Cephalic presentation

Exclusion Criteria:

• Any clinical contraindication to misoprostol as induction drug

• Age less than 18 years

• Contraindication to vaginal birth

• Nonreassuring fetal heart rate tracing

• Prior uterine surgery

• Active labor

• Active maternal bleeding

• Chorioamnionitis (infection)