A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis

• Status: Completed
• Trial end date: 2008-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The study objective is to investigate the efficacy of levocetirizine in reducing symptoms associated with seasonal allergic rhinitis and in improving rhinitis-related Quality of Life.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: UCB Pharma
• Treatments: Cetirizine; Levocetirizine

Criteria

Inclusion Criteria:

• Subjects with a history of SAR symptoms

• A positive skin prick test at least one grass allergen

• Moderate - severe SAR symptoms at baseline

• Women of childbearing potential must use a medically acceptable form of contraception

• 80% compliance on run in study medication and 80% compliance on completing the diary

Exclusion Criteria:

• The presence of any clinically significant comorbid disease which may interfere with the study assessments

• The presence of renal disease

• Pregnant or breastfeeding

• Subject is currently participating in another clinical trial

• Known hypersensitivity to piperazines or any of the excipients

• Intake of medications prohibited before the start of the trial

• Subjects who started or changed the dose of immunotherapy

• Rhinitis medicamentosa

• Subjects with a recent history (within the last 2 years) of drug or alcohol abuse