Overview

A Study Evaluating the Long-Term Safety of Elexacaftor Combination Therapy

Status:
Active, not recruiting
Trial end date:
2022-06-01
Target enrollment:
0
Participant gender:
All
Summary
This study will evaluate the long-term safety and tolerability of elexacaftor (ELX)/tezacaftor (TEZ)/ ivacaftor (IVA) triple combination (TC) in subjects with cystic fibrosis (CF) who are homozygous for F508del.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Vertex Pharmaceuticals Incorporated
Treatments:
Elexacaftor
Ivacaftor
Criteria
Key Inclusion Criteria:

- Completed study drug treatment in parent study (VX18-445-109); or had study drug
interruption(s) in parent study but completed study visits up to the last scheduled
visit of the Treatment Period in the parent study

Key Exclusion Criteria:

- History of study drug intolerance in parent study

Other protocol defined Inclusion/Exclusion criteria may apply