Overview

A Study Evaluating the Role of Oral Antibiotics in an Aim to Eradicate Carrier State of Carbapenem- Resistant Klebsiella Pneumonia (KPC).

Status:
Completed

Trial end date:
2012-01-01

Target enrollment:
0

Participant gender:
All

Summary

Klebsiella pneumonia, inhabitant of the digestive tract, is a frequent nosocomial pathogen. It is currently the fourth most common cause of pneumonia and fifth most common cause of bacteremia in intensive care patients (1-3). The aim of the present randomized controlled trial is to assess the efficacy of non-absorbable oral antibiotics in the eradication of the KPC carrier state.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Rambam Health Care Campus

Treatments:

Anti-Bacterial Agents
Colistin
Gentamicins
Polymyxins

Criteria

Inclusion Criteria:

- Inclusion Criteria

1. Patient identified as a KPC carrier.

2. Patient capable to understand and sign informed consent

3. Age > 18

4. Patient capable to receive oral medication

Exclusion Criteria:

- Exclusion Criteria:

1. Patient unable to sign informed consent

2. Age ≤ 18

3. Pregnant/lactating female

4. Patient not expected to survive > 2 weeks.

5. Patient unable or not allowed to receive oral medications

6. A known allergy to study drugs.