A Study Of PF-04449913 Administered Alone In Select Solid Tumors

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study examines the effect of a small molecule inhibitor to the Sonic Hedgehog pathway on select solid tumors.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pfizer

Criteria

Inclusion Criteria:

• Histological or cytological diagnosis of advanced/metastatic solid tumor

• Adequate Bone Marrow Function

• Adequate Renal Function

• Adequate Liver Function

Exclusion Criteria:

• Patients with known symptomatic brain metastases requiring steroids

• Current active treatment on another clinical trial

• Major surgery or radiation therapy within 4-weeks of starting study treatment