A Study On An Immunostimulant Antibody In Combination With Chemotherapy For Advanced Cancer Of The Pancreas

• Status: Completed
• Trial end date: 2011-01-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to seek evidence that activation of certain cells of the immune system will be safe and well tolerated in combination with cytotoxic chemotherapy. Preliminary evidence of clinical anti-tumor activity will be sought.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hoffmann-La Roche
• Collaborator: University of Pennsylvania
• Treatments: Antibodies; Antibodies, Monoclonal; Gemcitabine; Immunoglobulins; Pancrelipase

Criteria

Inclusion Criteria:

• 1st-line surgically incurable cancer of the pancreas

• ECOG(Eastern Cooperative Oncology Group) performance status 0-1

Exclusion Criteria:

• Previous systemic therapy for pancreas cancer

• History of cancer-associated blood clots

• History of autoimmune disease