A Study To Assess the Effects Of PF-04457845 On BOLD fMRI In Subjects With Post Traumatic Stress Disorder
Status:
Terminated
Trial end date:
2015-03-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to evaluate proof of mechanism of PF-04457845, using a
well-established neuroimaging paradigm including behavioral tasks selected to activate
neuro-circuitry relevant to Post Traumatic Stress Disorder. It is hypothesized that
PF-04457845 will modulate the Blood-oxygen-level dependent Functional Magnetic Resonance
Imaging signal from the relevant neuro-circuits in patients with Post Traumatic Stress
Disorder.