A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis
Status:
Recruiting
Trial end date:
2025-02-01
Target enrollment:
Participant gender:
Summary
CMTX-101 is a bacterial biofilm disrupting monoclonal antibody being developed as an
adjunctive therapy to standard of care antibiotics. The goal of this clinical trial is to
assess the safety and tolerability of CMTX-101 in people with cystic fibrosis (pwCF).
The main questions the study aims to answer are:
- Are single doses of CMTX-101 IV infusion safe and tolerated
- What is the pharmacokinetic (PK) profile of single doses of CMTX-101
- Do single doses of CMTX-101 induce development of anti-drug antibodies (ADA) and
neutralizing antibodies (Nabs)