A Study Using Subject-specific MRD to Adopt Treatment After HSCT for Subjects With MDS
Status:
Recruiting
Trial end date:
2026-12-01
Target enrollment:
Participant gender:
Summary
The goal of this interventional study is to evaluate if pre-emptive intervention using
Azacitidine and / or donor lymphocytes or tapering of immune suppression in measurable
residual disease (MRD) positive subjects can prevent clinical relapse. Participants will
undergo MRD surveillance and be subjected to intervention in case of MRD positivity. Results
will be compared with NMDSG14B, part one, in which MRD was analyzed in included patients
without recieving intervention.