A Study in Preterm Neonates With RDS to Compare CUROSURF® Administration Through LISA and Conventional Administration
Status:
Recruiting
Trial end date:
2025-09-30
Target enrollment:
Participant gender:
Summary
This study will compare the administration of porcine surfactant (poractant alfa, Curosurf®)
through a less invasive method (LISA) using a thin catheter, CHF 6440 (LISACATH®), during
non-invasive ventilation (CPAP, NIPPV, BiPAP) with an approved conventional surfactant
administration during invasive ventilation followed by rapid extubation in terms of short
term and mid-term safety and efficacy in spontaneously breathing preterm neonates with
clinical signs of respiratory distress syndrome (RDS).