A Study of 123I-CMICE-013 Radiopharmaceutical in Healthy Volunteers
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
The need exists for alternatives to 99mTc based perfusion radiotracers for cardiac patient
management. An alternative radiotracer, I123-CMICE-013, has been developed at the Canadian
Molecular Imaging Center of Excellence (C-MICE) at the University of Ottawa Heart Institute.
Initial testing results in rats and pigs suggest that in addition to being a
cyclotron-produced alternative to 99mTc tracers, I-123-CMICE-013 may be a superior tracer for
measuring myocardial perfusion.This Phase 1 study will study the safety and tolerability,
biodistribution, pharmacokinetics and radiation dosimetry, and distribution and localization
of I123-CMICE-013in healthy adult volunteers.