Overview

A Study of ADH 1 in Combination With Carboplatin, or Docetaxel or Capecitabine

Status:
Completed
Trial end date:
2009-11-01
Target enrollment:
Participant gender:
Summary
N-cadherin, a protein involved in blood vessel cell binding, is increased as cancer progresses, and is on the surface of many tumor cells. ADH-1 blocks N-cadherin. This study will test the safety and effects of the combination ADH-1 and carboplatin or ADH-1 and docetaxel or ADH-1 and capecitabine in subjects with specific incurable, solid tumors with a protein biomarker called N-cadherin.
Phase:
Phase 1
Details
Lead Sponsor:
Adherex Technologies, Inc.
Collaborator:
US Oncology Research
Treatments:
Capecitabine
Carboplatin
Docetaxel