A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal Neuralgia
Status:
Terminated
Trial end date:
2015-01-01
Target enrollment:
Participant gender:
Summary
Trigeminal neuralgia or tic douloureux is severe, often debilitating, facial pain that
significantly impairs the patient's quality of life and health. Stereotactic radiosurgery has
been shown to provide pain relief in majority of patients treated. However, a common side
effect of radiosurgery is facial numbness. Our goal is to maximize pain control while
minimizing side effects. To this end, the purpose of this study is to evaluate whether adding
a drug, amifostine, at the time of radiosurgery will protect patients from facial numbness.