Overview

A Study of Avutometinib and Defactinib in People With Thyroid Cancer

Status:
Recruiting
Trial end date:
2027-08-16
Target enrollment:
Participant gender:
Summary
The researchers are doing this study to find out if the combination of avutometinib and defactinib is an effective treatment for RAF dimer-driven radioiodine-refractory differentiated thyroid cancer or anaplastic thyroid cancer. The researchers will also test whether avutometinib and defactinib is a safe treatment that causes few or mild side effects.
Phase:
Phase 2
Details
Lead Sponsor:
Memorial Sloan Kettering Cancer Center
Collaborator:
Verastem, Inc.